I-Salicin, eyaziwa nangokuthi i-willow alcohol ne-salicin, inefomula ethi C13H18O7. Itholakala kakhulu emagxolweni nasemaqabunga ezitshalo eziningi ze-willow kanye ne-poplar, isibonelo, amagxolo e-purple willow angaqukatha kufika ku-25% we-salicin. Ingenziwa nge-chemical synthesis. I-salicinogen ne-salicylic acid ingatholakala emchameni 15-30min ngemuva kokuphathwa ngomlomo, ngakho-ke, ine-antipyretic, analgesic and anti-inflammatory, anti-rheumatic effects. Ngenxa yokuthi ukuguqulwa okunjalo akuhlali njalo, ngakho-ke inani layo lokwelapha liphansi kune-salicylic acid. Iphinde ibe nomphumela obabayo wesisu kanye ne-anesthetic yendawo. Ingasetshenziswa futhi njenge-reagent ye-biochemical. Kuwukuhlakanipha ukukhetha i-China Active Salicin. SingaI-Active Salicin Factory; Umkhiqizi we-Salicin osebenzayo; Izimboni ezisebenzayo zeSalicin.
I-salicin iyikristalu emhlophe; ukunambitheka okubabayo; iphoyinti elincibilikayo 199-202℃, ukuzungezisa okuqondile [α] -45.6° (0.6g/100cm3 i-ethanol engenamanzi); I-1g encibilika emanzini angu-23ml, 3ml amanzi abilayo, 90ml ethanol, 30ml 60° ethanol, encibilika kusixazululo se-alkali, i-pyridine ne-glacial acetic acid, engancibiliki ku-ether, i-chloroform. Isixazululo esinamanzi sibonisa ukungathathi hlangothi ephepheni le-litmus. Alikho iqembu lamahhala le-phenolic hydroxyl ku-molecule, lingele-phenolic glycosides. I-Hydrolyzed by dilute acid noma i-almond enzyme ebabayo, ingakhiqiza i-glucose ne-salicyl alcohol. I-molecular formula ye-salicyl alcohol yi-C7H8O2; iyikristalu yenaliti engenambala e-rhomboidal; indawo encibilikayo 86~87℃; i-sublimation ku-100 ℃; i-soluble emanzini ne-benzene, i-soluble kalula ku-ethanol, i-ether ne-chloroform; umbala obomvu lapho uhlangana ne-sulfuric acid.
I-Salicin inemiphumela ye-antipyretic kanye ne-analgesic, futhi yayisetshenziswa ekwelapheni i-rheumatism esikhathini esidlule, kodwa yathathelwa indawo ezinye izidakamizwa. Ngenxa yokuthi ingakhiqiza utshwala obu-salicylic ngemva kwe-hydrolysis, ingafakwa kalula i-oxid ukuze ikhiqize i-salicylic acid, ngakho-ke yayiwumthombo oyinhloko wezidakamizwa ze-synthetic salicylic acid, futhi manje imboni yezokwelapha isisebenzise indlela yokwenziwa yokwenza i-salicylic acid.
I-Salicin, isithako esilwa nokuvuvukala, eyaziwa nangokuthi i-Willowbark extract, inezindawo zokulwa nokuvuvukala ezithatha indawo ephelele ye-salicylic acid, ebangela ukucasuka kwesikhumba.
Ukusebenza kwe-salicin
Ukusebenza kwe-salicin: I-Salicin iyi-ejenti elwa nokuvuvukala eyenziwe ngamagxolo omzane, agaywa umzimba abe yi-salicylic acid. Ngokwencazelo ye-Wikipedia, iyafana ngokwemvelo ne-aspirin futhi ngokwesiko isetshenziselwa ukuphulukisa amanxeba nobuhlungu bemisipha. Nakuba ukuguqulwa kwe-salicin ku-salicylic acid emzimbeni womuntu kudinga ama-enzyme, i-salicin ye-topical nayo iyasebenza ngoba inezici ezifanayo zokulwa nokuvuvukala ku-aspirin futhi isetshenziselwa ukukhiqizwa kwemikhiqizo yezinduna ukuze ikhulule induna nokunye ukucasuka kwesikhumba.
Isikhathi sokuthumela: Feb-15-2023