Isithasiselo esibizwa nge-5-hydroxytryptophan (5-HTP) noma i-osetriptan sithathwa njengenye yezindlela zokwelapha ikhanda kanye nemigraines. Umzimba uguqula le nto ibe i-serotonin (5-HT), eyaziwa nangokuthi i-serotonin, i-neurotransmitter elawula imizwa nobuhlungu.
Amazinga aphansi e-serotonin avame ukubonakala kubantu abanokucindezeleka, kodwa abaphethwe yi-migraine kanye nabaphethwe yikhanda elingapheli bangase babe namazinga aphansi e-serotonin phakathi naphakathi kokuhlaselwa. Akucaci ukuthi kungani i-migraines ne-serotonin kuxhunywe. Ithiyori ethandwa kakhulu ukuthi ukuntuleka kwe-serotonin kwenza abantu bazizwele kakhulu ebuhlungu.
Ngenxa yalokhu kuxhumana, izindlela ezimbalwa zokwandisa umsebenzi we-serotonin ebuchosheni zivame ukusetshenziselwa ukuvimbela i-migraines nokwelapha ukuhlaselwa okunamandla.
I-5-HTP iyi-amino acid eyenziwe ngumzimba ku-amino acid ebalulekile i-L-tryptophan futhi kufanele itholakale ekudleni. I-L-tryptophan itholakala ekudleni okufana nembewu, ubhontshisi wesoya, i-turkey noshizi. Ama-Enzyme ngokwemvelo aguqula i-L-tryptophan ibe yi-5-HTP, ebese iguqula i-5-HTP ibe yi-5-HT.
Izithasiselo ze-5-HTP zenziwe ngesitshalo sezokwelapha saseNtshonalanga Afrika i-Griffonia simplicifolia. Lesi sengezo sisetshenziselwe ukwelapha ukucindezeleka, i-fibromyalgia, i-chronic fatigue syndrome, kanye nokulahlekelwa isisindo, kodwa abukho ubufakazi obuphelele bezinzuzo zayo.
Uma ucabangela i-5-HTP nanoma yisiphi isithasiselo semvelo, kubalulekile ukuqonda ukuthi le mikhiqizo ingamakhemikhali. Uma uzithatha ngoba zinamandla ngokwanele ukuba nomthelela omuhle empilweni yakho, khumbula ukuthi zingaba namandla ngokwanele ukuba zibe nemiphumela emibi.
Akucaci ukuthi izithasiselo ze-5-HTP zinenzuzo kuma-migraines noma ezinye izinhlobo zekhanda elibuhlungu. Sekukonke, ucwaningo lulinganiselwe; ezinye izifundo zibonisa ukuthi kuyasiza, kuyilapho ezinye zingabonisi mphumela.
Ucwaningo lwe-Migraine lusebenzise imithamo ye-5-HTP kusukela ku-25 kuya ku-200 mg ngosuku kubantu abadala. Okwamanje awukho umthamo ocacile noma onconyiwe walesi sengezo, kodwa kufanele kuqashelwe ukuthi imithamo ephezulu ihlotshaniswa nemiphumela emibi kanye nokusebenzisana kwezidakamizwa.
I-5-HTP ingase ihlanganyele neminye imithi, kuhlanganise ne-carbidopa, esetshenziselwa ukwelapha isifo sika-Parkinson. Ingase futhi ihlanganyele nama-triptan, ama-SSRI, nama-monoamine oxidase inhibitors (ama-MAOI, elinye ikilasi lama-antidepressants).
I-Tryptophan kanye ne-5-HTP supplements ingase ingcoliswe yisithako semvelo i-4,5-tryptophanione, i-neurotoxin eyaziwa nangokuthi i-Peak X. Imiphumela yokuvuvukala ye-Peak X ingabangela ubuhlungu bemisipha, i-cramping, nomkhuhlane. Imiphumela yesikhathi eside ingase ihlanganise ukulimala kwemisipha nezinzwa.
Ngenxa yokuthi le khemikhali iwumkhiqizo wokusabela kwamakhemikhali hhayi ukungcola noma ukungcola, ingatholakala kuma-supplements ngisho noma ilungiselelwe ngaphansi kwezimo zokuhlanzeka.
Kubalulekile ukuxoxa ngokuthatha noma yiziphi izithasiselo nodokotela wakho noma usokhemisi ukuze uqiniseke ukuthi ziphephile kuwe futhi ngeke zihlanganyele neminye imithi yakho.
Khumbula ukuthi izithasiselo zokudla nezamakhambi azenzanga ucwaningo oluqinile nokuhlolwa njengemithi etholakala ekhawuntareni kanye nekadokotela, okusho ukuthi ucwaningo olusekela ukusebenza kahle nokuphepha kwazo lulinganiselwe noma aluphelele.
Izithasiselo namakhambi emvelo zingakhanga, ikakhulukazi uma zingenayo imiphumela emibi. Eqinisweni, amakhambi emvelo afakazele ukuthi ayasebenza ezifweni eziningi. Kunobufakazi bokuthi izithako ze-magnesium zinganciphisa imvamisa nokuqina kokuhlaselwa kwe-migraine. Kodwa-ke, akucaci ukuthi i-5-HTP inenzuzo kuma-migraines.
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U-Teri Robert Teri Robert ungumlobi, uthisha onesineke, kanye nommeli wesineke onguchwepheshe be-migraines kanye nekhanda elibuhlungu.