I-Black cohosh, eyaziwa nangokuthi impande yenyoka emnyama noma impande ye-rattlesnake, idabuka eNyakatho Melika futhi inomlando omude wokusetshenziswa e-United States. Eminyakeni engaphezu kwamakhulu amabili, aboMdabu baseMelika baye bathola ukuthi izimpande ze-black cohosh zisiza ukukhulula amajaqamba nokuya esikhathini, okuhlanganisa i-flusher eshisayo, ukukhathazeka, ukushintshashintsha kwemizwelo nokuphazamiseka kokulala. Impande emnyama ye-hemp isasetshenziselwa lezi zinhloso namuhla.

Isithako esiyinhloko esisebenzayo sempande i-terpene glycoside, futhi impande iqukethe ezinye izithako ze-bioactive, kuhlanganise ne-alkaloids, i-flavonoids ne-tannic acid. I-Black cohosh ingakhiqiza imiphumela efana ne-estrogen futhi ilawule ibhalansi ye-endocrine, engasiza ekudambiseni izimpawu zokunqamuka kokuya esikhathini njengokuqwasha, ukushisa okushisayo, ubuhlungu beqolo nokulahlekelwa ngokomzwelo.

Njengamanje, ukusetshenziswa okuyinhloko kwe-black cohosh extract ukukhulula izimpawu ze-perimenopausal. Iziqondiso ze-American College of Obstetricians and Gynecologists mayelana nokusetshenziswa kwamakhambi ezimpawu ze-perimenopausal zithi angasetshenziswa kuze kube yizinyanga eziyisithupha, ikakhulukazi ukukhulula ukuphazamiseka kokulala, ukuphazamiseka kwemizwelo kanye nokushisa okushisayo.

Njengamanye ama-phytoestrogens, kukhona ukukhathazeka mayelana nokuphepha kwe-black cohosh kwabesifazane abanomlando noma umlando womndeni womdlavuza webele. Nakuba kudingeka uphenyo olwengeziwe, ucwaningo olulodwa lwe-histological kuze kube manje lubonise ukuthi i-cohosh emnyama ayinawo umphumela ovuselela i-estrogen kumangqamuzana omdlavuza webele we-estrogen-receptor, futhi i-cohosh emnyama itholakale yandisa umphumela we-tamoxifen we-antitumor.

Ukukhishwa kwe-black cohoshibuye isetshenziselwe ukwelapha ukuphazamiseka kwemizwa yemifino okubangelwa ukunqamuka kokuya esikhathini, futhi inomthelela omuhle ezinkingeni zokuzala zabesifazane ezifana ne-amenorrhea, izimpawu zokunqamuka kokuya esikhathini njengobuthakathaka, ukucindezeleka, ukushisa okushisayo, ukungazali noma ukuzala. Ibuye isetshenziselwe ukwelapha izifo ezilandelayo: i-angina pectoris, umfutho wegazi ophakeme, isifo samathambo, isifuba somoya, ukulunywa yinyoka, ikholera, ukudlikizela, i-dyspepsia, i-gonorrhea, isifuba somoya kanye nokukhwehlela okungamahlalakhona okunjengokukhwehlela, umdlavuza nesibindi nezinso.

I-Black cohoshakutholakalanga ukusebenzisana nezinye izidakamizwa ngaphandle kwe-tamoxifen. Umphumela ovame kakhulu otholakala ezivivinyweni zomtholampilo kwakuwukungakhululeki kwamathumbu. Ngemithamo ephezulu, i-black cohosh ingabangela isiyezi, ikhanda elibuhlungu, isicanucanu nokuhlanza. Ngaphezu kwalokho, abesifazane abakhulelwe akufanele basebenzise i-black cohosh ngoba ingavusa ukufinyela kwesibeletho.