Izindaba - Ingabe i-extract ye-melon ebabayo inganciphisa umfutho wegazi?

Iyini i-extract ye-melon ebabayo?

I-Bitter melon extract itholakala esithelweni seMomordica charantia futhi iyisithako semvelo esisetshenziswa kakhulu emithini yendabuko yaseShayina kanye nemikhiqizo yezempilo yesimanje. Ithole ukunakwa ngenxa yokusebenza kwayo kahle ekulawuleni ushukela egazini, ekukhuthazeni impilo ye-metabolic, nasekuqiniseni amasosha omzimba. I-Bitter melon extract icebile ngezithako eziningi ezisebenzayo futhi inezinzuzo eziningi empilweni yabantu.

Ingxenye eyinhloko

1. AmaSaponins (iCharantin)
• Inomphumela wokwehlisa ushukela egazini, ingenye yezingxenye ezibalulekile ze-bitter melon extract.

2. I-insulin yesitshalo (i-Polypeptide-p)
• Ingxube efana ne-insulin evela ezitshalweni esiza ekulawuleni amazinga kashukela egazini.

3. Ama-Momordicoside
• Izithako ezisebenzayo ezinemiphumela yokulwa nokuvuvukala kanye ne-antioxidant.

4. Amavithamini namaminerali
• Kunovithamini C omningi, i-vitamin A, i-potassium, kanye ne-iron, okusiza empilweni iyonke.

5. Ama-Flavonoid
• Inikeza imiphumela yokulwa nama-antioxidant futhi ivikela amaseli ekulimaleni kwama-free radical.

Ushukela Ophansi Wegazi

Indlela yokusebenza kwe-bitter melon extract ekwehliseni ushukela wegazi ihilela kakhulu imithethonqubo ehlukahlukene yomzimba, ayikwazi nje ukuthinta ngqo i-glucose metabolism, kodwa futhi ithuthukise ukusebenza kahle kwe-insulin.

1. Lingisa isenzo se-insulin
• I-insulin yesitshalo (i-Polypeptide-p):
• I-Bitter melon extract iqukethe i-polypeptide efana ne-insulin, engalingisa umsebenzi we-insulin futhi ikhuthaze i-glucose emaseli ukuze ithole amandla, ngaleyo ndlela inciphise ukugcwala kwe-glucose egazini.
• Ifaneleka kakhulu iziguli ezingakwazi ukukhipha i-insulin eyanele noma ezingasebenzi kahle kwe-insulin.

2. Khulisa ukuzwela kwe-insulin
• Thuthukisa ukumelana ne-insulin:
• Izithako ezisebenzayo eziku-batter melon, njenge-saponins (Charantin), zingathuthukisa ukuzwela kweseli ku-insulin ngokulawula ama-insulin receptors eseli, okusiza ekumunceni nasekusebenziseni ushukela egazini ngendlela ephumelela kakhulu.
• Kubantu abanesifo sikashukela sohlobo lwesibili, ukumelana ne-insulin kuyinkinga enkulu, futhi i-bitter melon extract ingasebenza ngokunciphisa lokhu ukumelana.

3. Vimbela ukumuncwa kukashukela
• Kunciphisa ukumuncwa kwe-glucose yisisu:
• Izingxenye ezithile ze-bitter melon extract zingavimbela umsebenzi we-α-glucosidase emathunjini. Le enzyme inesibopho sokuphula ama-carbohydrate ayinkimbinkimbi abe ushukela, futhi ukuvimbela umsebenzi wayo kunciphisa izinga lokunyuka koshukela egazini, ikakhulukazi ngesikhathi sokuphakama kwangemva kokudla.

4. Lawula ama-enzyme aguqula i-glucose ibe amandla
• Ikhabe elibabayo elikhishwe lingaba:
Yenza kusebenze i-AMPK (i-AMP-activated protein kinase): I-AMPK iyisishintshi sokulawula amandla eseli esikhuthaza ukuguqulwa kwe-glucose ibe amandla futhi sinciphise ukukhiqizwa kwe-glucose esibindini.
• Kuvimbela i-gluconeogenesis esibindini, kunciphisa ukukhishwa kwe-glucose eningi egazini esibindini.

5. I-Anti-oxidation ivikela i-pancreas
• Ama-polyphenols nama-flavonoid ku-bitter melon extract anemiphumela yokulwa ne-antioxidant futhi angavikela amaseli e-pancreatic beta ekucindezelekeni kwe-oxidative.
• Impilo yamaseli e-beta ibalulekile ekukhiqizweni kwe-insulin, futhi i-bitter melon extract ingakhuthaza ngokungaqondile ukukhiqizwa kwe-insulin okuvamile.

6. Nciphisa umthelela wokuvuvukala okungapheli kushukela wegazi
• Isithako esisebenzayo esiku-bitter melon singavimbela ukukhishwa kwezinto ezibangela ukuvuvukala emzimbeni, njenge-TNF-α, kanti ukuvuvukala okungapheli kuhlobene kakhulu nokumelana ne-insulin.
• Ngokunciphisa amazinga okuvuvukala, i-bitter melon extract ingathuthukisa ukusebenza kwe-glucose iyonke.