1. Isifinyezo se-Aframomum Melegueta

II-Aframomum Melegueta, edabuka eNtshonalanga Afrika, inephunga le-cardamom kanye nokunambitheka okufana nopelepele. Yayisetshenziswa kabanzi njengenye indlela esikhundleni sepelepele lapho upelepele wawunqabile eYurophu ngekhulu le-13, futhi yayibizwa ngokuthi “imbewu yezulu” ngoba yayibhekwa njengomusa ovela ezulwini.

I-Aframomum Melegueta inamagama ahlukene njengezinhlamvu zepharadesi, i-Atare (ngesiYoruba), i-chitta (isiHausa), noma i-Guinea pepper, iyimbewu eyodwa enamandla amaningi okuphulukisa futhi izinzuzo zayo esintwini zibonakala zingenamkhawulo.

I-Aframomum melegueta (Grains of Paradise) isetshenziswa ekwelapheni izifo ezithathelwanayo ezifana nokutheleleka komgudu womchamo okubangelwa yi-Escherichia coli, i-Klebsiella pneumoniae, i-Enterococcus faecalis, i-Staphylococcus saprophyticus, i-Proteus mirabilis, i-Staphylococcus aureus engamelana ne-methicillin, i-Salmonella spp, kanye ne-Shigella spp. Ibonisa ithemba elithile ekulawuleni amafutha ngemithamo engase isetshenziswe emikhiqizweni yokudla kanye nengxube yemithi.

2. Indawo Yokusabalalisa

I-Aframomum Melegueta（I-Paradise Pepper）, egama layo langempela yi-African Cardamom, eyaziwa nangokuthi i-Peppercorn, i-Guinea Pepper, i-Melegueta Pepper, i-Paradise Pepper, noma i-Alligator Pepper, iyisitshalo esihlala isikhathi eside somndeni wakwaZingiberaceae. Sivela ezindaweni ezisogwini lwaseNtshonalanga Afrika. Sivula izimbali ezinsomi, ezimise okwecilongo, sithela ama-pod amade angu-5-7 cm futhi siqukethe imbewu ebomvu-nsundu. I-Peppery, futhi ngoba yaba yindawo yokuqala yepelepele. Manje ivame ukusetshenziswa ngaphakathi e-Afrika. Yisinye isinongo se-Silk Road esinyamalale ekudleni kwanamuhla kwase-Eurasia, kodwa sisasetshenziswa ezingxenyeni zaseNtshonalanga naseNyakatho Afrika, futhi siyisitshalo esibalulekile semali ezingxenyeni zase-Ethiopia. I-African cardamom, edabuka ezindaweni ezisogwini zaseNtshonalanga Afrika, kubonakala sengathi yayisetshenziswa eduze neGhana yanamuhla ekuqaleni futhi kamuva yathunyelwa kwezinye izindawo ezisemachwebeni empumalanga ye-Afrika noma ogwini lwaseMedithera ukuze ihwebe nge-Silk Road. Isinongo, esasithandwa kakhulu ekuphekeni kwaseYurophu ngesikhathi sokuqala kwe-Renaissance, sanyamalala kancane kancane etafuleni ngekhulu leshumi nesishiyagalombili sabe sesinyamalala ezimakethe zaseYurophu, sathathelwa indawo yi-cardamom nezinye izinongo ezithunyelwa zivela e-Asia emhlabeni jikelele.

3. Isingeniso se-6-Paradol

I-Paradol, i-metabolite ye-shogaol engenabuhlungu ngokunciphisa i-enzyme, yaziwa ukuthi inemisebenzi yokulwa nokuvuvukala. Okutholakele kwamanje kwe-in vitro kubonisa ukuthi izakhiwo zokuvimbela ze-6-paradol ekwelapheni ukuvuvukala kwe-neuroinflammation ku-microglia zihlobene nekhono lokwelapha le-in vivo le-ischemia yobuchopho. Ukusebenza kahle kwe-6-paradol ekuvikeleni i-neuroinfraction ku-cerebral ischemia nakho kunokusetshenziswa kwayo okungenzeka ekwelapheni ezinye izifo ze-CNS lapho ukuvuvukala kwe-neuroinfraction kuyisici se-pathological. Ngaphezu kwalokho, uma i-6-paradol iboniswa ukuthi isebenza kahle kwezinye izifo ze-CNS, impahla yayo engenabuhlungu inenzuzo yemiphumela emibi embalwa esiswini, okusho ukuthi ingathathwa isikhathi eside, ngokungafani nezingxenye ze-ginger noma ze-ginger okungenzeka ukuthi i-6-shogaol.

I-paradol engu-6iyisidakamizwa esinamandla kakhulu sokulwa nomalaleveva futhi iyisici esiyinhloko salesi sifo.I-Zookwesibiliichibi le-metabolite.

I-6-Paradol (igama le-IUPAC [1-(4-hydroxy-3-methoxyphenyl) decan-3-one]) iyinhlanganisela ye-phenolic ebukhali etholakala ezitshalweni zomndeni wakwaZingiberaceae, njengejinja kanye nezinhlamvu zepharadesi (I-Aframomum meleguetanoma upelepele we-alligator). Njengoba kushiwo kwenye indawo, izifundo ezimbalwa zibike imisebenzi ye-antioxidant, anti-inflammatory, cytotoxic, anti-hyperlipidaemic, hypoglycaemic, kanye ne-antitumor yamakhemikhali ahlukene e-paradol kumamodeli ahlukahlukene ezilwane.

4. Umsebenzi Womkhiqizo

1. I-Aframomum melegueta extract ingasetshenziswa njenge-Spice kanye ne-ejenti yokunambitha;

2. I-Aframomum melegueta extract ingasetshenziswa njengesikhuthazi esinuka kamnandi; ekwelapheni ukukhwehlela kanye ne-bronchitis; elwa namathambo; ye-dyspepsia;

3. Kutholakale ukuthi i-Aframomum melegueta extract ikhuthaza ukwehla kwesisindo ngokuthuthukisa ukusebenza komzimba okusheshayo;

4. I-Aframomum melegueta extract ingakhulisa ikhono lobulili njenge-aphrodisiac.

Izinkomba：https://www.zhitiquan.com

I-Aframomum Melegueta (Grains of Paradise)——Oludare Temitope Osuntokun

https://doi.org/10.1371/journal.pone.0120203

https://doi.org/10.1016/j.phyplu.2021.100208

NgobaI-Aframomum Melegueta, sicela usithinte. Sikulindele lapha nganoma yisiphi isikhathi!