I-Phosphatidylserine yigama elinikezwa uhlobo lwe-phospholipid olutholakala ngokwemvelo emzimbeni.

I-Phosphatidylserine idlala indima eminingana emzimbeni. Okokuqala, yakha ingxenye ebalulekile yolwelwesi lwamaseli.

Okwesibili i-phosphatidylserine itholakala ku-myelin sheath evala izinzwa zethu futhi inesibopho sokudluliselwa kwemizwa.

Kukholelwa futhi ukuthi iyi-cofactor ezinhlobonhlobo zama-enzyme ahlukene athinta ukuxhumana emzimbeni.

Lezi zici zihlangene zisho ukuthi i-Phosphatidylserine inendima ebaluleke kakhulu okufanele iyidlale uma kukhulunywa ngesimiso sezinzwa esiyinhloko.

Nakuba kuyizinto zemvelo ezingakhiqizwa emzimbeni noma ezitholakala ekudleni kwethu, njengoba sikhula amazinga ethu e-Phosphatidylserine angaqala ukwehla. Uma lokhu kwenzeka, ochwepheshe bakholelwa ukuthi kuthinta uhlelo lwethu lwezinzwa, okuholela ekuwohlokeni kokuqonda kanye nokuncipha kokusabela.

Izifundo ngemiphumela yokukhulisa amazinga e-Phosphatidylserine emzimbeni ngokufaka izithako ezengeziwe zibonisa izinzuzo eziningi ezijabulisayo njengoba sizobona.

Izinzuzo zePhosphatidylserine

Ngokusho kwe-Alzheimer's Society, umuntu oyedwa kwabayisithupha abaneminyaka engaphezu kwengu-80 unesifo sokuwohloka komqondo. Nakuba amathuba okuxilongwa okunjalo ekhula njengoba iminyaka ikhula, kungathinta nezisulu ezisencane kakhulu.

Njengoba inani labantu likhula, ososayensi batshale isikhathi nemali ocwaningweni lwe-dementia, kanye nokusesha izindlela zokwelapha ezingaba khona. I-Phosphatidylserine iyinhlanganisela enjalo futhi ngenxa yalokho sazi okuningi ngezinzuzo ezingaba khona zokwengeza. Nazi ezinye zezinzuzo ezingaba khona ezithakazelisayo ezikhonjiswe ocwaningweni lwakamuva…

Umsebenzi Othuthukisiwe Wokuqonda

Mhlawumbe ucwaningo olujabulisa kakhulu olwenziwe nge-Phosphatidylserine, eyaziwa nangokuthi i-PtdSer noma i-PS nje, lugxile ezinzuzweni ezingaba khona zokumisa noma ngisho nokuguqula izimpawu zokuncipha kwengqondo.

Kokunye ukuhlola, iziguli ezikhulile ezingu-131 zanikezwa isithasiselo esiqukethe i-Phosphatidylserine ne-DHA noma i-placebo. Ngemva kwamasonto angu-15 womabili amaqembu ahlolwe ngendlela yokuhlola ukusebenza kwawo kwengqondo. Okutholakele kwembule ukuthi labo abathatha i-Phosphatidylserine babone ukuthuthuka okukhulu ekukhumbuleni nasekufundeni ngomlomo. Bakwazi futhi ukukopisha izimo eziyinkimbinkimbi ngesivinini esikhulu. Olunye ucwaningo olufanayo olusebenzisa i-Phosphatidylserine lubonise ukwanda okungu-42% kwekhono lokukhumbula amagama agcinwe ngekhanda.

Kwenye indawo, iqembu lamavolontiya anenkinga yokukhumbula elineminyaka ephakathi kuka-50 no-90 ubudala anikezwe i-Phosphatidylserine supplementation isikhathi esingamasonto ayi-12. Ukuhlolwa kubonise ukuthuthuka ekukhumbuleni inkumbulo kanye nokuguquguquka kwengqondo. Ucwaningo olufanayo luphinde lwathola ngokungalindelekile ukuthi labo bantu abathatha i-supplement babone ukwehla okuncane nokunempilo komfutho wegazi labo.

Okokugcina, ocwaningweni olubanzi, cishe iziguli ezingu-500 ezineminyaka ephakathi kuka-65 no-93 zaqashwa e-Italy. Kwanikezwa i-Phosphatidylserine isikhathi sezinyanga eziyisithupha ezigcwele ngaphambi kokuba kuhlolwe izimpendulo. Intuthuko ebalulekile ngokwezibalo ibonwe hhayi nje kuphela ngokwemigomo yokuqonda, kodwa futhi nezici zokuziphatha.

Kuze kube manje, ubufakazi bubonakala busikisela ukuthi i-Phosphatidylserine ingaba nendima ebalulekile ekulweni nokulahlekelwa yinkumbulo okuhlobene nokuguga kanye nokwehla okuvamile kobukhali bengqondo.

Ulwa Nokucindezeleka

Kunezinye izifundo ezisekela umbono wokuthi i-Phosphatidylserine ingasiza ekuthuthukiseni isimo sengqondo nokuvikela ukucindezeleka.

Kulokhu, iqembu labantu abadala abasebasha abahlushwa ukucindezeleka lanikezwa i-300mg ye-Phosphatidylserine noma i-placebo nsuku zonke inyanga yonke. Ochwepheshe babike ukuthi labo bantu abathatha lesi sithasiselo bathole "ukuthuthuka kwemizwa".

Olunye ucwaningo lwemiphumela ye-Phosphatidylserine esimweni sengqondo luhilele iqembu labesifazane asebekhulile abahlushwa ukucindezeleka. Iqembu elisebenzayo lanikezwa ama-300mg e-Phosphatidylserine ngosuku futhi ukuhlolwa okuvamile kwalinganisa umthelela wezithasiselo empilweni yengqondo. Abahlanganyeli bathole ukuthuthuka okuphawulekayo ezimpawini zokucindezeleka kanye nokuziphatha okuvamile.

Ukusebenza Kwezemidlalo Okuthuthukisiwe

Nakuba i-Phosphatidylserine ithole ukunakwa okukhulu ngendima yayo engaba khona ekuxazululeni izimpawu zokuguga, kutholakale nezinye izinzuzo ezingaba khona. Lapho abantu bezemidlalo abanempilo bethola lesi sithasiselo kubonakala sengathi ukusebenza kahle kwezemidlalo kungase kube khona.

Abadlali begalofu, isibonelo, baboniswe ukuthi bathuthukisa umdlalo wabo ngemva kokunikeza i-Phosphatidylserine, kuyilapho ezinye izifundo zithole ukuthi abantu abasebenzisa i-Phosphatidylserine babona amazinga aphansi kakhulu okukhathala ngemva kokuzivocavoca. Ukusetshenziswa kwe-Phosphatidylserine engu-750mg ngosuku kuboniswe nokuthuthukisa amandla okuzivocavoca kwabagibeli bamabhayisikili.

Kolunye ucwaningo oluthakazelisayo, amadoda aphilile aneminyaka ephakathi kuka-18 no-30 acelwa ukuba aqedele ukuhlolwa kwezibalo ngaphambi nangemva kohlelo lokuqeqeshwa kokumelana okukhulu. Ochwepheshe bathole ukuthi labo bantu abanikezwa i-Phosphatidylserine baqede izimpendulo cishe ngo-20% ngokushesha kuneqembu lokulawula, futhi benza amaphutha ancishiswe ngo-33%.

Ngakho-ke kuye kwaphakanyiswa ukuthi i-Phosphatidylserine ingaba nendima ekucijiseni ukusabela komzimba, isheshise ukululama ngemva kokuqina komzimba kanye nokugcina ukunemba kwengqondo ngaphansi kokucindezeleka. Ngenxa yalokho, i-Phosphatidylserine ingaba nendawo ekuqeqeshweni kwabadlali abangochwepheshe.

Ukunciphisa Ukucindezeleka Komzimba

Uma sizivocavoca, umzimba ukhipha ama-hormone okucindezeleka. Yilawa ma-hormone angathinta ukuvuvukala, ubuhlungu bemisipha kanye nezinye izimpawu zokuziqeqesha ngokweqile.

Kokunye ukuhlola abantu besilisa abaphilile banikezwa u-600mg we-Phosphatidylserine noma i-placebo, ukuze kuthathwe nsuku zonke izinsuku eziyi-10. Abahlanganyeli babe sebethatha imihlangano yokugibela amabhayisikili eqinile ngenkathi impendulo yomzimba wabo kulo msebenzi ilinganiswa.

Kwabonakala ukuthi iqembu le-Phosphatidylserine lanciphisa amazinga e-cortisol, i-hormone yokucindezeleka, ngakho lalulama ngokushesha ekuzivocavoceni. Ngakho-ke kuye kwaphakanyiswa ukuthi i-Phosphatidylserine ingasiza ekuvikeleni izingozi zokuziqeqesha ngokweqile ezitholwa abantu abaningi bezemidlalo abangochwepheshe.

Yehlisa Ukuvuvukala

Ukuvuvukala kubangelwa yizimo eziningi zempilo ezingathandeki. Kuye kwaboniswa ukuthi ama-fatty acids kumafutha enhlanzi angasiza ekuvikeleni ukuvuvukala okungapheli, futhi siyazi ukuthi i-DHA kumafutha esibindi se-cod ingasebenza ngokubambisana ne-Phosphatidylserine. Ngakho-ke akufanele kumangaze ukuthi ezinye izifundo zibonisa ukuthi i-Phosphatidylserine ingasiza ekuvikeleni ukuvuvukala.

Umonakalo we-Oxidative

Ochwepheshe abaningi bakholelwa ukuthi umonakalo we-oxidative uyisici esiyinhloko ekuqaleni kwesifo sokuwohloka komqondo. Kuphinde kuhlotshaniswe nomonakalo ojwayelekile wamaseli futhi kuye kwahlotshaniswa nezimo eziningi zempilo ezingathandeki. Lesi esinye sezizathu zokwanda kwesithakazelo kuma-antioxidants eminyakeni yamuva nje, njengoba kutholakale ukuthi asiza ekulweni nama-free radicals angase abangele umonakalo.

Izifundo zikhombisile ukuthi i-Phosphatidylserine ingase idlale indima lapha futhi, njengoba ubufakazi bezakhiwo zayo zokulwa ne-antioxidant sebutholakele.

Ingabe Kufanele Ngithathe Izithasiselo Ze-Phosphatidylserine?

Amanye ama-Phosphatidylserine angatholakala ngokudla ukudla okunempilo nokuhlukahlukene, kodwa ngokufanayo, imikhuba yokudla yesimanje, ukukhiqizwa kokudla, ukucindezeleka kanye nokuguga okuvamile kusho ukuthi ngokuvamile asitholi amazinga e-Phosphatidylserine adingekayo ukuze ubuchopho bethu busebenze kahle.

Impilo yanamuhla ingaba yinto ecindezelayo maqondana nomsebenzi kanye nempilo yomndeni, futhi ukwanda kokucindezeleka kuholela ekwandeni kwesidingo se-Phosphatidylserine, okusho ukuthi ngokuvamile izimpilo zethu ezicindezelayo ziholela ekunciphiseni kwalesi sici.

Ngaphezu kwalokhu, ukudla kwesimanje, okunamafutha amancane/i-cholesterol ephansi kungantula kufika ku-150mg we-Phosphatidylserine edingekayo nsuku zonke kanti ukudla kwemifino kungantula kufika ku-250mg. Ukudla okune-Omega-3 fatty acid deficiency kunganciphisa izinga le-Phosphatidylserine ebuchosheni ngo-28% ngaleyo ndlela kuthinte ukusebenza kwengqondo.

Ukukhiqizwa kokudla kwanamuhla kunganciphisa amazinga azo zonke i-Phosphatidylserine okuhlanganisa ne-Phosphatidylserine. Ucwaningo lukhombisile ukuthi asebekhulile bangazuza kakhulu ngokwandisa amazinga abo e-Phosphatidylserine.

Ukuguga kwandisa izidingo zobuchopho ze-Phosphatidylserine kuyilapho kudala ukungasebenzi kahle kwe-metabolic. Lokhu kusho ukuthi kunzima kakhulu ukuthola okwanele ngokudla kuphela. Ucwaningo lukhombisile ukuthi i-Phosphatidylserine ithuthukisa ukukhubazeka kwenkumbulo okuhlobene nokuguga futhi ivimbela ukuwohloka kwemisebenzi yobuchopho, ngakho-ke ingaba yisengezo esibalulekile esizukulwaneni esidala.

Uma uzimisele ukusekela impilo yengqondo njengoba ukhula, i-Phosphatidylserine ingase ibe enye yezithako ezijabulisa kakhulu ezitholakalayo.

Isiphetho

I-Phosphatidylserine ivela ngokwemvelo ebuchosheni kodwa izimpilo zethu zansuku zonke ezicindezelayo, kuhlangene nokuguga kwemvelo kungandisa isidingo sethu salokho. Izithasiselo ze-Phosphatidylserine zingazuzisa ubuchopho ngezindlela eziningi futhi izifundo zesayensi zibonise ukusebenza kwayo ekuthuthukiseni inkumbulo, ukugxilisa ingqondo nokufunda, okuholela empilweni ejabulisayo nenempilo kanye nobuchopho.